New to GLP-1?

As a newcomer to GLP-1, understanding its role and incorporating it into your healthcare routine has become a pivotal aspect of my journey towards improved well-being. Exploring the benefits and potential impact of GLP-1 on your health is an essential part of a newfound approach to managing overall health and wellness.

What is GLP-1?

GLP-1 (glucagon-like peptide-1) medications are a class of drugs used to treat type 2 diabetes. They work by mimicking the effects of GLP-1, a natural hormone that stimulates insulin release, lowers glucagon secretion, and slows gastric emptying. These actions help regulate blood sugar levels. GLP-1 medications also contribute to weight loss by reducing appetite and promoting a feeling of fullness.

Examples of GLP-1 medications include exenatide, liraglutide, and dulaglutide. They are often prescribed alongside other diabetes treatments or as part of a comprehensive approach to managing the condition.

Why Take GLP-1 for Weightloss?

GLP-1, or glucagon-like peptide-1, is increasingly recognized for its potential in weight loss management. This hormone plays a crucial role in regulating blood sugar and appetite. By enhancing satiety and slowing down the digestive process, GLP-1 can contribute to reduced calorie intake and, consequently, weight loss. Medications that mimic or enhance the action of GLP-1 are commonly prescribed for individuals struggling with obesity or excess weight.

These medications can be a valuable addition to a comprehensive weight loss strategy, especially for those who have difficulty achieving sustainable results through diet and exercise alone. The use of GLP-1 for weight loss is often considered in the context of a holistic approach to health, promoting long-term benefits beyond just shedding pounds.


GLP-1-based medications are generally considered safe and effective for weight loss when used under the supervision of a healthcare professional. These medications work by mimicking the action of the natural hormone GLP-1, which regulates blood sugar and appetite. They are commonly prescribed for individuals with type 2 diabetes, and weight loss is often an additional benefit observed in those using these medications. However, like any medication, GLP-1 agonists may have potential side effects, and individual responses can vary. It’s crucial to consult with a healthcare provider to assess whether GLP-1-based therapies are suitable for specific health conditions and to monitor any potential side effects during use. As with any medical intervention, the decision to use GLP-1 for weight loss should be made in collaboration with a qualified healthcare professional.

Whether your doctor will prescribe a GLP-1 agonist for you depends on various factors, including your medical history, current health condition, and weight loss goals. GLP-1 medications are often prescribed for individuals with type 2 diabetes, and some of these medications have been approved for weight management in people without diabetes.

GLP-1s, natural hormones released from the gut after eating, serve to increase insulin production and maintain blood sugar levels within the normal range. They also contribute to the sensation of fullness post-meal. GLP-1 receptor agonists, which mimic these effects, result in individuals feeling fuller both during and between meals, experiencing enhanced glucose levels, and a reduction in preoccupation with thoughts about food.

For your doctor to prescribe a GLP-1 agonist like Wegovy, specific criteria must be met. These medications are intended for the treatment of obesity, and to be eligible for Wegovy, you must meet FDA requirements, which include having a body mass index (BMI) of 30 or higher or a BMI of 27 or higher with a weight-related complication, such as high blood pressure or high cholesterol. Additionally, eligibility criteria involve being unable to achieve weight loss through lifestyle changes and having a history of fluctuating weight. It is recommended to have a conversation with your doctor to determine if GLP-1 medications are suitable for your individual circumstances.

Certainly. Embracing a “yes” response, it’s crucial to recognize that enduring weight management necessitates lifestyle adjustments within any weight-loss program. This holds true even if previous attempts at weight loss did not hinge solely on lifestyle changes. Experts align on the notion that integrating healthy dietary modifications and elevating daily physical activity alongside the use of GLP-1 medications forms an optimal combination. This amalgamation not only fosters substantial weight loss but also enhances overall well-being, mitigating the risk of weight regain upon discontinuation of the medication. Furthermore, adhering to a healthful eating regimen and ensuring adequate hydration can effectively preempt or alleviate initial side effects, such as nausea, headaches, and fatigue, commonly associated with the initiation of these medications.

In 2005, GLP-1 medications were initially developed to help people with type 2 diabetes control their blood sugar levels. Recent studies of these medications further revealed that they had the potential to help with weight loss.

Mayo Clinic